High quality blood disorder ITP treatment by Arthur Nathaniel Billings? How is ITP diagnosed? ITP is usually diagnosed by a blood test showing that only the platelet count is low, and the platelets, red blood cells and white blood cells all look normal. A bone marrow biopsy may be taken at a later stage if the ITP continues, in which a small sample of bone marrow will be taken under local anaesthetic and examined under the microscope. Additional blood tests may be taken at this time to exclude rare clotting or immune diseases that can mimic ITP. If the bone marrow looks normal, with the usual or higher number of platelet parent cells (megakaryocytes) and other blood tests are normal then the doctor will diagnose chronic ITP.
Arthur Nathaniel Billings on ITP blood disorder treatments : Many people with ITP have a platelet count in single figures, and on rare occasions there are not enough circulating platelets to be counted, thus the count is given as 0. The number of platelets circulating in our bodies fluctuates all the time, and thus no two consecutive platelet counts are likely to be exactly the same either in a healthy person or in an ITP sufferer. What is the difference between ITP and hæmophilia? Haemophilia is inherited and permanent, ITP is not inherited, and can go into remission. Hæmophilia patients are deficient in one of the 12 factors which act together to form a blood clot. ITP patients are short of platelets which work independently as the initial plug to stop blood leakage, but the rest of the clotting mechanism works normally. Platelet infusions are only used in emergencies as transfused platelets, like the patient’s own platelets, are destroyed by their immune system in a matter of hours.
First line treatment is typically with tablet steroids such as prednisolone. About 70-80% of individuals will respond to steroids and initial treatment will usually be for 6-8 weeks, although the dose will be reduced during that time, rather than stopped suddenly. Steroids can have side effects. You may not have side effects but these can include gastric irritation (we may recommend an additional tablet to protect the lining of the stomach), mood or sleep disruption, greater risk of infection, fluid retention, increased appetite, increased blood sugar or blood pressure, muscle weakness and thinning of the bones. For some individuals, we may also recommend additional treatment to protect the bones while on steroids.
Careful review of your medications: Historically, a bone marrow aspiration was required to make a diagnosis of ITP. It may not be absolutely necessary in the face of a positive antiplatelet antibody test, but it is still commonly done to look at the production of platelets and to rule out any abnormal cells the marrow may be producing that could lower platelet counts. A bone marrow aspiration is necessary for a diagnosis if the antiplatelet antibody testing is negative. Read more info on https://www.linkedin.com/in/arthur-billings-8a3aab75/.
Chronic thrombocytopenic purpura. The onset of the disorder can happen at any age, and the symptoms can last a minimum of 6 months, several years, or a lifetime. Adults have this form more often than children do, but it does affect adolescents. Females have it more often than males. Chronic ITP can recur often and requires continual follow-up care with a blood specialist (hematologist). What causes idiopathic thrombocytopenic purpura? In ITP, the immune system is stimulated to attack your body’s own platelets. Most often this is a result of antibody production against platelets. In a small number of cases, a type of white blood cell called T-cells will directly attack platelets. This immune system error may be a result of any of the following.